Now fully revised and up-to-date, Expert DDx: Brain and Spine, second edition, quickly guides you to the most likely differential diagnoses based on key imaging findings and clinical information. It presents more than 250 of the top differential diagnoses across a broad spectrum of central nervous system diseases, encompassing specific anatomic locations, generic imaging findings, modality-specific findings, and clinically based indications. Every reader will have expert guidance for defining and reporting useful, actionable differential diagnoses that lead to definitive findings in every area of the brain and spine.
New to this Edition:-
- Includes expanded differential considerations, new cases, and new images throughout
- Covers hot topics such as different variants of medulloblastoma, convexal subarachnoid hemorrhage, and hyperdense basal ganglia
- Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Key Features
- Presents at least eight clear, sharp, succinctly annotated images for each diagnosis; a list of diagnostic possibilities sorted as common, less common, and rare but important; and brief, bulleted text offering helpful diagnostic clues
- Separates adult and pediatric DDx lists for even faster reference
Author Information
By Miral D. Jhaveri, MD, Associate Professor, Division Head, Neuroradiology, Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, Illinois; Karen L. Salzman, MD, Professor of Radiology and Imaging Sciences, Neuroradiology Section Chief and Fellowship Director, Leslie W. Davis Endowed Chair in Neuroradiology, University of Utah School of Medicine, Salt Lake City, Utah ; Jeffrey S. Ross, MD, Senior Associate Consultant, Neuroradiology Division, Department of Radiology, Mayo Clinic Arizona, Professor of Radiology, Mayo Clinic College of Medicine, Phoenix, Arizona ; Kevin R. Moore, MD, Pediatric Radiologist and Neuroradiologist, Vice Chair, Department of Medical Imaging, Primary Children's Hospital, Salt Lake City, Utah ; Anne G. Osborn, MD, FACR, University Distinguished Professor and Professor of Radiology and Imaging Sciences, William H. and Patricia W. Child Presidential Endowed Chair in Radiology, University of Utah School of Medicine, Salt Lake City, Utah and Chang Yueh Ho, MD, Assistant Professor of Clinical Neuroradiology, Division Chief, Neuroradiology, Indiana University School of Medicine, Director, Pediatric Neuroimaging, Riley Hospital for Children, Indianapolis, Indiana
Table of Contents:-
SKULL AND BRAIN
Scalp, Skull
Anatomically Based Differentials
Skull Normal Variants
Scalp Mass, Child
Scalp Mass, Adult
Congenital Anomalies of Skull Base
Sellar/Parasellar Mass With Skull Base Invasion
Generic Imaging Patterns
"Hair on End"
Thick Skull, Generalized
Thick Skull, Localized
Thin Skull, Generalized
Thin Skull, Localized
Lytic Skull Lesion, Solitary
Multiple Lucent Skull Lesions
Sclerotic Skull Lesion, Solitary
Sclerotic Skull Lesions, Multiple
Clinically Based Differentials
Macrocephaly
Microcephaly
Meninges
Anatomically Based Differentials
Dural Calcification(s)
Dural-Based Mass, Solitary
Dural-Based Masses, Multiple
Falx Lesions
Generic Imaging Patterns
Thick Dura/Arachnoid, Generalized
Pial Enhancement
Dural Tail Sign
Ventricles, Periventricular Regions
Anatomically Based Differentials
Ventricles, Normal Variants
Choroid Plexus Lesions, Child
Choroid Plexus Lesions, Adult
Ependymal/Subependymal Lesions
Lateral Ventricle Mass
Thick Septum Pellucidum
Foramen of Monro Mass
3rd Ventricle Mass, Anterior
3rd Ventricle Mass, Body/Posterior
Cerebral Aqueduct/Periaqueductal Lesion
4th Ventricle Mass, Child
4th Ventricle Mass, Adult
Generic Imaging Patterns
Bubbly Appearing Intraventricular Mass
Ependymal Enhancement
Large Ventricles
Small Ventricles
Asymmetric Lateral Ventricles
Irregular Lateral Ventricles
Periventricular Enhancing Lesions
Modality-Specific Imaging Findings
Intraventricular Calcification(s)
Periventricular Calcification(s)
Periventricular T2/FLAIR Hyperintense Lesions
Extraaxial Spaces and Subarachnoid Cisterns
Anatomically Based Differentials
Cistern, Subarachnoid Space Normal Variants
Epidural Mass
Enlarged Sulci, Generalized
Effaced Sulci, Generalized
Interhemispheric Fissure Cysts
CPA Mass, Adult
Cystic CPA Mass
Prepontine Cistern Mass
Ventral Foramen Magnum Mass
Dorsal Foramen Magnum Mass
Generic Imaging Patterns
Solitary Enhancing Cranial Nerve
Multiple Enhancing Cranial Nerves
CSF-Like Extraaxial Fluid Collection
Convexal Subarachnoid Hemorrhage
CSF-Like Extraaxial Mass
Sulcal/Cisternal Enhancement
Fat in Sulci/Cisterns/Ventricles
Pneumocephalus
Modality-Specific Imaging Findings
Extraaxial Flow Voids
T1 Hyperintense CSF
FLAIR Hyperintense Sulci
T2 Hypointense Extraaxial Lesions
Hyperdense CSF
Hyperdense Extraaxial Mass(es)
Hypodense Extraaxial Mass(es)
Brain Parenchyma, General
Generic Imaging Patterns
Multiple Enhancing Lesions, General
Ring-Enhancing Lesion, Solitary
Ring-Enhancing Lesion, Multiple
Solitary Cystic Parenchymal Mass, General
CSF-Like Parenchymal Lesion(s)
Cyst With Nodule
Fat and Fat-Like Lesion(s)
Modality-Specific Imaging Findings
Solitary Parenchymal Calcification
Multiple Parenchymal Calcifications
Solitary Hyperdense Parenchymal Lesion
Multiple Hyperdense Parenchymal Lesions
Solitary Hypodense Parenchymal Lesion
Multiple Hypodense Parenchymal Lesions
Multiple Brain Hyperintensities (T2/FLAIR), Common
Multiple Brain Hyperintensities (T2/FLAIR), Less Common
Multiple Brain Hyperintensities (T2/FLAIR), Rare but Important
Multiple Hypointense Foci on T2
Multiple Hypointense Foci on GRE/SWI
T1/T2 Hyperintense Parenchymal Lesions
T1 Hypointense, T2 Hyperintense Parenchymal Lesions
T1/T2 Isointense Parenchymal Lesions
Restricted Diffusion, General
Restricted Diffusion, Cortex
Restricted Diffusion, Basal Ganglia
T1 Hyperintense Parenchymal Lesion(s)
Clinically Based Differentials
Brain Tumor in Newborn/Infant
Brain Tumor in Child > 1 Year
Epilepsy, Child
Epilepsy, Adult
Supratentorial Brain Parenchyma
Anatomically Based Differentials
Asymmetric Cerebral Hemispheres
Thick Cortex
Thin Cortex
Focal Cortical Mass
Cortical Hyperintensity T2/FLAIR
Cortical Enhancement
Solitary White Matter Lesion
Confluent White Matter Lesions
Thin Corpus Callosum
Abnormal Shape/Configuration of Corpus Callosum
Corpus Callosum Holes
Corpus Callosum Lesion Without Mass Effect
Corpus Callosum Mass
Corpus Callosum Splenium Lesion
Medial Temporal Lobe Lesion
Hippocampal Lesion
Basal Ganglia Calcification
Hyperdense Basal Ganglia
Hypodense Basal Ganglia
T1 Hyperintense Basal Ganglia
T2 Hyperintense Basal Ganglia
Enlarged Perivascular Spaces
Perivascular Space Enhancing Lesions
Bilateral Basal Ganglia Lesions
Putamen Lesion(s)
Globus Pallidus Lesion(s)
Unilateral Thalamic Lesion
Bithalamic Lesions
Pulvinar Sign
Tectal (Quadrigeminal Plate) Lesion
Infratentorial Brain Parenchyma
Anatomically Based Differentials
Large Brainstem
Small Brainstem
T2 Hyperintense Brainstem, Focal
T2 Hyperintense Brainstem, Diffuse
Midbrain Lesion
Pontine Lesion
Medulla Lesion
Middle Cerebellar Peduncle Lesion(s)
Cerebellar Atrophy
Cerebellar Hemisphere Mass
Vermis Mass
Low Cerebellar Tonsils
Generic Imaging Patterns
Cystic-Appearing Posterior Fossa Lesion
Clinically Based Differentials
Posterior Fossa Neoplasm, Adult
Posterior Fossa Neoplasm, Pediatric
Sella/Juxtasellar, Pineal Region
Anatomically Based Differentials
Pineal Region Mass, General
Pineal Gland Mass
Quadrigeminal Cistern Mass
Pineal + Suprasellar Lesions
Sella/Pituitary Normal Variants
Sellar/Juxtasellar Calcification
Enlarged Pituitary Gland
Intrasellar Lesion
Cystic Intrasellar Mass
Suprasellar Mass, Child
Suprasellar Mass, Adult
Suprasellar Cystic Mass
Calcified Suprasellar Mass
Enhancing Suprasellar Mass
Absent/Thin Infundibular Stalk
Thick Infundibular Stalk
Hypothalamus Lesion
Modality-Specific Imaging Findings
Hyperdense Suprasellar Mass
T1 Hyperintense Suprasellar Mass
Arteries
Anatomically Based Differentials
Multifocal Arterial Narrowing
Vessel Wall Abnormalities
Fusiform Arterial Enlargement
Modality-Specific Imaging Findings
Hyperattenuating ("Dense") Artery
Veins, Venous Sinuses
Anatomically Based Differentials
Dural Sinus Lesion, General
Enlarged Cortical Veins
Enlarged Deep (Medullary/Ependymal) Veins
Unilateral Cavernous Sinus Mass
Bilateral Cavernous Sinus Lesions
Meckel Cave Lesion
Modality-Specific Imaging Findings
Hyperdense Dural Sinus
GRE/SWI Venous Abnormalities
Cranial Nerves
Clinically Based Differentials
Hemifacial Spasm
Sensorineural Hearing Loss in Adult
Sensorineural Hearing Loss in Child
Monocular Vision Loss
Bitemporal Heteronymous Hemianopsia
Homonymous Hemianopsia
Oculomotor, Trochlear, or Abducens Neuropathy
Trigeminal Neuralgia
Complex Cranial Nerve IX-XII Neuropathy
Horner Syndrome
SPINE
Transspatial
Anatomically Based Differentials
Cervical, Chronic Posttraumatic Abnormality
Cervical, Lower, Posttraumatic Bony Abnormality
Thoracic Bony Trauma
Lumbar Bony Trauma
Generic Imaging Patterns
Scoliosis
Kyphosis
Kyphoscoliosis, Child
Platyspondyly, Diffuse
Sacral Mass, Adult
Sacrococcygeal Mass, Pediatric
Sacral Deformity
Clinically Based Differentials
Acute Back Pain/Radiculopathy, Postoperative
Chronic Back Pain/Radiculopathy, Postoperative
Acute Upper Extremity Pain/Weakness
Lower Extremity Pain
Back Pain, Adult
Back Pain, Pediatric
Craniovertebral Junction
Anatomically Based Differentials
Craniocervical Junction Acute Injury
CVJ Abnormality, General
Craniovertebral Junction Soft Tissue Abnormality
Generic Imaging Patterns
C1-C2 Instability
Odontoid Deformity
Vertebral Body, Posterior Elements
Anatomically Based Differentials
Congenital Vertebral Anomalies
Cervical Bony Fusion
Generic Imaging Patterns
Flattened Vertebral Body, Solitary
Flattened Vertebral Body, Multiple
Dysmorphic Vertebral Body
Enlarged Vertebral Body/Posterior Element
Enlarged Neural Foramen
Vertebral Body Scalloping/Widened Canal
Spondylolisthesis
Bony Lesion, Aggressive
Fracture, Vertebral Body
Facet Abnormality, Nontraumatic
Fracture, Posterior Element
Pedicle Abnormality
Modality-Specific Imaging Findings
Enlarged Vertebral Body, Soap Bubble Expansion
Vertebral Body Sclerosis, Focal
Vertebral Body Sclerosis, Diffuse
Vertebral Body Thickened Bony Trabeculae
Vertebral Body, T1 Hyperintense Signal, Diffuse
Vertebral Body, T1 Hyperintense Signal, Focal
Vertebral Body, T1 Hypointense Signal, Diffuse
Vertebral Body, T1 Hypointense Signal, Focal
Intervertebral Disc, Endplate
Generic Imaging Patterns
Disc Contour Abnormality
Intervertebral Disc/Endplate Irregularity
Vertebral Endplate Contour Abnormality
Modality-Specific Imaging Findings
Intervertebral Disc, T1 Hypointense
Intervertebral Disc, T2 Hyperintense
Vertebral Endplate Signal Abnormality
Extradural
Anatomically Based Differentials
Epidural Mass, Spine
Ventral/Lateral Paraspinal Mass
Generic Imaging Patterns
Paraspinal Muscle Abnormality
Extradural Lesions, Multiple
Extradural Lesion, No Enhancement
Extradural Lesion, Solid Enhancement
Modality-Specific Imaging Findings
Soft Tissue Calcification, Paraspinal
Extradural, Normal Marrow Signal
Extradural, Abnormal Marrow Signal
Extradural Lesion, T1 Hyperintense
Extradural Lesion, T1 Hypointense
Extradural Lesion, T2 Hyperintense, T1 Isointense
Extradural Lesion, T2 Hypointense, T1 Hypointense
Clinically Based Differentials
Lumbar Soft Tissue Mass, Pediatric
Intradural Extramedullary
Anatomically Based Differentials
Cauda Equina Enhancement, Diffuse
Subarachnoid Space Narrowing
Intradural Extramedullary, Leptomeningeal Enhancement
Generic Imaging Patterns
Intradural Extramedullary Lesion, No Enhancement
Intradural Extramedullary Lesion, Solid Enhancement
Intradural Lesion, Serpentine
Intradural Extramedullary Lesion, Multiple
Modality-Specific Imaging Findings
Intradural Extramedullary Lesion, Ring/Peripheral Enhancement
Intradural Extramedullary Lesion, T1 Hyperintense
Intradural Extramedullary Lesion, T1 Hypointense
Intradural Extramedullary Lesion, T1 Hypointense, T2 Hypointense
Intradural Extramedullary Lesion, T2 Hyperintense, T1 Isointense"
Clinically Based Differentials
Cauda Equina Syndrome
Intramedullary
Anatomically Based Differentials
Intramedullary Mass
Conus Abnormality
Generic Imaging Patterns
Cord, Small/Atrophic
Intramedullary Lesions, Multiple
Intramedullary Lesion, Solid Enhancement
Intramedullary Lesion, No Enhancement
Intramedullary Lesion, Diffuse/Ill-Defined Enhancement
Intramedullary Lesion, Ring/Peripheral Enhancement
Modality-Specific Imaging Findings
Intramedullary Lesion, T1 Hypointense, T2 Hypointense
Intramedullary Lesion, T1 Hypointense
Intramedullary Lesion, T2 Hyperintense, T1 Isointense
Intramedullary Lesion, T1 Hyperintense
Cord Lesion, T2 Hyperintense, Ventral
Cord Lesion, T2 Hyperintense, Dorsal
Cord Lesion, T2 Hyperintense, Central
Clinically Based Differentials
Myelopathy
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